I came across this suggestion from Unclutterer and thought I'd pass it along. I tried something like this when I first got married and it lasted about two weeks. It's a great idea, though, and I'm inspired to try it again.
"Don’t feel you need to take on cleaning your entire house all in one weekend. At Chez Doland, we deep clean the kitchen and dining room on Monday, Bathrooms on Tuesday, Bedrooms on Wednesday, Living and family rooms on Thursday, and Friday is for the foyer, garage, and laundry room. After a 10 minute general pick up around the house, we focus for 20 minutes on the targeted room."